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Epicardial Adipose Tissue in Cardiovascular Disease
(Springer, 2019)
Cardiovascular disease (CVD) is the maincause of morbidity and mortality in industrialized countries, despite the evolution of treatments and revascularization strategies.Obesity, also accompanied by a chronicinflammatory ...
Human periprostatic adipose tissue: its influence on prostate cancer cells
(Karger, 2012-06)
Background/Aims: Adipose microenvironment is involved in signaling pathways that influence prostate cancer (PCa) progression. However, the role of human periprostatic adipose tissue (PPAT) from patients with benign prostatic ...
White Adipose Tissue and Circadian Rhythm Dysfunctions in Obesity: Pathogenesis and Available Therapies
(Karger, 2017-04)
A combined neuroendocrine, metabolic, and chronobiological view can help to better understand the multiple and complex mechanisms involved in obesity development and maintenance, as well as to provide new effective approaches ...
Periprostatic adipose tissue microenvironment: metabolic and hormonal pathways during prostate cancer progression
(Frontiers Media, 2022-04)
The periprostatic adipose tissue (PPAT) is a site of invasion of prostate cancer (PCa) and is part of the microenvironment. It was shown that PPAT secretes factors and fatty acids (FAs) that alter the microenvironment of ...
Adipose tissue inflammation and metabolic syndrome: The proactive role of probiotics
(Dr Dietrich Steinkopff Verlag, 2018-07)
Chronic low-grade inflammation that characterized metabolic syndrome can contribute to the development of the metabolic dysfunctions involved in the pathogenesis of its comorbidities. Adipose tissue is a complex organ that ...
Severe hyperprolactinemia promotesbrown adipose tissue whitening andaggravates high fat diet inducedmetabolic imbalance
(Frontiers Media, 2022-06)
The association of high serum prolactin and increased body weight is positive but controversial, therefore we hypothesized that additional factors such as diets and the impact of prolactin on brown adipose tissue may ...
Behavior of Metalloproteinases in Adipose Tissue, Liver and Arterial Wall: An Update of Extracellular Matrix Remodeling
(Molecular Diversity Preservation International, 2019-02)
Extracellular matrix (ECM) remodeling is required for many physiological and pathological processes. Metalloproteinases (MMPs) are endopeptidases which are able to degrade different components of the ECM and nucleus matrix ...
Time course of adipose tissue dysfunction associated with antioxidant defense, inflammatory cytokines and oxidative stress in dyslipemic insulin resistant rats
(Royal Society of Chemistry, 2015-01)
The dysfunctional adipose tissue of rats fed a sucrose-rich diet was investigated following the time course of the development of oxidative stress, changes in proinflammatory cytokines and adiponectin levels, and their ...
Renal peritumoral adipose tissue undergoes a browning process and stimulates the expression of epithelial-mesenchymal transition markers in human renal cells
(Springer Nature, 2022)
Tumor cells can interact with neighboring adipose cells and adipocyte dedifferentiation appears to be an important aspect of tumorigenesis. We evaluated the size of adipocytes in human adipose explants from normal (hRAN) ...